Optical frequency combs (OFCs) are revolutionary light sources characterized by discrete and equally spaced spectral lines, and they have found widespread applications in metrology, spectroscopy, and communications. In the early stages, OFCs were realized using mode-locked lasers. With advancements in the fabrication of high-quality factor (Q) microresonators and the increasing demand for miniaturized and integrable photonic chips, microresonator-based OFCs, commonly referred to as microcombs, have been developed. Although early studies of microcombs primarily focused on single microresonators or a few resonators, a significant breakthrough occurred in 2021 when it was theoretically predicted that light propagating in the topological edge channel of an array of ring resonators could generate nested frequency combs known as topological OFCs. Since then, the field of topological OFCs has progressed rapidly, with experimental observations made in 2024. This Perspective will introduce the history of OFCs, placing particular emphasis on the emergence and development of topological OFCs, as well as exploring the research challenges and opportunities associated with them.