To deploy deep neural networks on edge hardware, highly efficient inference schemes are necessary that retain high accuracy. This work presents W16A16, a high precision (16-bit), fast speed, low energy quantization method. On a widely applied microcontroller architecture Armv7E-M, our proposed approach achieves faster speed and lower energy consumption on layer- and model-level compared to alternative quantization schemes. We analyze the architecture of Armv7E-M, explain the underlying principles behind the performance advantages of 16-bit approaches, and evaluate the empiric quantization errors for regression and classification tasks, as well as empiric time- and energy consumption in MCU deployment. We observe ca. 10 times lower quantization errors compared to 8-bit quantization schemes while achieving similar or better inference times and energy consumption.