Using first-principles calculations, we show that altermagnetism emerges in (LaVO₃)ₙ/(LaNiO₃)ₘ superlattices, with (n,m) = (1,1), (2,2) and (2,4), from the interplay of interfacial charge transfer and octahedral tilts. Charge transfer drives the system towards the V⁴⁺ and Ni²⁺ configuration, turning the otherwise paramagnetic nickelate layers into a magnetically active sublattice. The resulting C-type antiferromagnetic order, combined with a⁻b⁺c⁻ or a⁻b⁻c⁻ octahedral tilts, links opposite-spin sublattices only through nonsymmorphic operations, yielding a d-wave spin splitting without spin-orbit coupling. Within DFT+U, the splitting reaches 118 meV in the insulating (LVO)₁/(LNO)₁ superlattice, about twice that calculated for bulk LaVO₃, and decreases as the nickelate layers become thicker. Our findings indicate that this splitting is hosted by both the V and Ni sublattices, with nearly half of its weight on oxygen 2p states through p-d covalency. Interfacial charge transfer thus emerges as a design principle for engineering altermagnetism in oxide heterostructures.